Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSH | P09668 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425794 | 0.87 | METAP2 (0.43) | METAP2CTSKTSHRALDH1A1NPSR1 | |
| SCHEMBL11021965 | 0.87 | METAP2 (0.43) | METAP2CTSKTSHRALDH1A1NPSR1 | |
| SCHEMBL16732371 | 0.85 | METAP2 (0.40) | METAP2CTSKTSHRALDH1A1NPSR1 | |
| SCHEMBL4713295 | 0.83 | METAP2 (0.41) | METAP2CTSKTSHRALDH1A1NPSR1 | |
| SCHEMBL8784684 | 0.82 | METAP2 (0.40) | METAP2CTSKTSHRALDH1A1NPSR1 | |
| SCHEMBL1009487 | 0.81 | L3MBTL1 (0.39) | METAP2CTSKTSHRALDH1A1NPSR1 | |
| SCHEMBL4717390 | 0.81 | METAP2 (0.39) | METAP2CTSKTSHRALDH1A1NPSR1 | |
| SCHEMBL8329848 | 0.81 | METAP2 (0.39) | METAP2CTSKTSHRALDH1A1NPSR1 | |
| SCHEMBL9376051 | 0.78 | TSHR (0.41) | METAP2CTSKTSHRALDH1A1NPSR1 | |
| SCHEMBL9219750 | 0.77 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730204-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SRL (IT) | 2011-08-10 | — | — | EP | disclosed |
| US-7544748-B2 | Components and catalysis for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2009-06-09 | — | — | US | disclosed |
| US-20070208150-A1 | Components and Catalysis for the Polymerization of Olefins | BASELL POLIOLEFINE ITALIA S.R.L (IT) | 2007-09-06 | — | — | US | disclosed |
| EP-1730204-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005097841-A1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2005-10-20 | — | — | WO | disclosed |