Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.45 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.45 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.45 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38662196 | 0.87 | HRH3 (0.49) | TRPV6JAK2JAK1JAK3NTRK1 | |
| SCHEMBL14375256 | 0.87 | TRPV6 (0.58) | TRPV6JAK2JAK1JAK3HRH3 | |
| SCHEMBL12767180 | 0.84 | TRPV6 (0.56) | TRPV6JAK2JAK1JAK3HRH3 | |
| SCHEMBL16622446 | 0.83 | TRPV6 (0.55) | TRPV6JAK2JAK1JAK3HRH3 | |
| SCHEMBL12727199 | 0.83 | TRPV6 (0.55) | TRPV6JAK2JAK1JAK3HRH3 | |
| Hydrochloric Acid SCHEMBL16612764 | 0.82 | TRPV6 (0.54) | TRPV6JAK2JAK1JAK3HRH3 | |
| SCHEMBL23589183 | 0.82 | HRH3 (0.67) | TRPV6HRH3PIK3CACD274PIK3CD | |
| SCHEMBL23589171 | 0.82 | TRPV6 (0.53) | TRPV6JAK2JAK1JAK3HRH3 | |
| SCHEMBL18713082 | 0.81 | TRPV6 (0.57) | TRPV6JAK2JAK1JAK3HRH3 | |
| SCHEMBL29122965 | 0.81 | CCR5 (0.51) | TRPV6HRH3TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057696-A1 | HETEROARYL COMPOUND AND APPLICATION THEREOF | 隆泰申医药科技(南京)有限公司 | 2021-04-01 | — | — | WO | disclosed |