Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6967654 | 0.96 | TAAR1 (0.44) | MAPTALDH1A1NPC1RAB9ANOS3 | |
| SCHEMBL5737404 | 0.85 | TAAR1 (0.54) | MAPTALDH1A1NPC1RAB9ANOS3 | |
| SCHEMBL5248789 | 0.85 | MAPT (0.41) | MAPTALDH1A1NPC1RAB9ANOS3 | |
| SCHEMBL23179843 | 0.85 | TAAR1 (0.43) | MAPTALDH1A1NPC1RAB9ANOS3 | |
| SCHEMBL23178806 | 0.82 | ALDH1A1 (0.48) | MAPTALDH1A1NPC1RAB9ANOS3 | |
| SCHEMBL6937021 | 0.82 | ESR2 (0.41) | MAPTALDH1A1NPC1RAB9ANOS3 | |
| SCHEMBL6983649 | 0.81 | MAPT (0.40) | MAPTALDH1A1NPC1RAB9ANOS3 | |
| SCHEMBL8164187 | 0.81 | MAPT (0.46) | MAPTALDH1A1NPC1RAB9ANOS3 | |
| SCHEMBL5737830 | 0.81 | MAPT (0.39) | MAPTALDH1A1NPC1RAB9ANOS3 | |
| SCHEMBL5735950 | 0.81 | NPC1 (0.39) | MAPTALDH1A1NPC1RAB9ANOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971171-A1 | OXAZOLINE COMPOUND, SYNTHESIS METHOD THEREFOR AND APPLICATION THEREOF | Nankai University (CN) | 2022-03-23 | — | — | EP | disclosed |
| WO-2021057852-A1 | OXAZOLINE COMPOUND, SYNTHESIS METHOD THEREFOR AND APPLICATION THEREOF | 南开大学 | 2021-04-01 | — | — | WO | disclosed |
| CN-1131945-A | Arthropodicidal oxazolines and thiazolines | DU PONT (US) | 1996-09-25 | — | — | CN | disclosed |