Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789519 | 0.87 | TAAR1 (0.40) | TAAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL23178721 | 0.86 | TAAR1 (0.41) | TAAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL23179843 | 0.85 | TAAR1 (0.43) | TAAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL23178803 | 0.85 | MAPT (0.41) | TAAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL5248789 | 0.85 | MAPT (0.41) | TAAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL23178806 | 0.82 | ALDH1A1 (0.48) | TAAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8164187 | 0.81 | MAPT (0.46) | TAAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL8656596 | 0.81 | MAPT (0.39) | TAAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL5737830 | 0.81 | MAPT (0.39) | TAAR1MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL5735950 | 0.81 | NPC1 (0.39) | TAAR1MAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1390356-B1 | ARYLISOXAZOLINE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2006-05-31 | — | — | EP | disclosed |
| EP-1390356-A1 | ARYLISOXAZOLINE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF AS PESTICIDES | Bayer CropScience GmbH (DE) | 2004-02-25 | — | — | EP | disclosed |
| US-6670307-B2 | Such as 2-(2,6-difluorophenyl)-4-(4-(2-ethoxypyridin-5-yl) phenyl)oxazoline; for administration to livestock | HOECHST SCHERING AGREVO GMBH (DE) | 2003-12-30 | — | — | US | disclosed |
| US-6645984-B2 | Mixtures of insecticides, miticides, nematocides, attractants, sterilizers, nematocides, fungicides or molluscides, used for protecting plants and/or seeds, or seals, paints, lubricants for metal working, drilling or cutting oil additives | AVENTIS CROPSCIENCE GMBH (DE) | 2003-11-11 | — | — | US | disclosed |
| EP-1087967-B1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-20030114501-A1 | Arylisoxazoline derivatives, processes for their preparation and their use as pesticides | MERIAL, INC. | 2003-06-19 | — | — | US | disclosed |
| WO-2002076956-A1 | ARYLISOXAZOLINE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2002-10-03 | — | — | WO | disclosed |
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | BAYER CROPSCIENCE AG (DE) | 2002-06-06 | — | — | US | disclosed |
| US-6265350-B1 | CONTROLLING HARMFUL FUNGI, INSECTS, ACARINA, MOLLUSKS AND NEMATODES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| EP-1087967-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | Aventis CropScience GmbH (DE) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065901-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | MT-CO1, OXA1L, MT-CO3 | TAAR1 628/4885MAPT 3869/4885ALDH1A1 127/4885 |
| US-20030114501-A1 | Arylisoxazoline derivatives, processes for their preparation and their use as pesticides | CBR1, CBR3, CYP4X1 | TAAR1 336/4885MAPT 4728/4885ALDH1A1 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.