SCHEMBL23181

SCHEMBL23181

C=CCOc1nc(OCC=C)nc(OCC=C)n1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.55
MAPT P10636 3/20 0.55
HSD17B10 Q99714 2/20 0.36
POLB P06746 1/20 0.36
CDK1 P06493 1/20 0.35
CCNB1 P14635 1/20 0.35
MGMT P16455 1/20 0.35
CCNA2 P20248 1/20 0.35
CDK2 P24941 1/20 0.35
CCNA1 P78396 1/20 0.35
CA12 O43570 6/20 0.33
CA9 Q16790 6/20 0.33
CA1 P00915 5/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
FGFR1 P11362 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL20395887 0.97 MAPK1 (0.53) MAPK1MAPTHSD17B10POLBCDK1
SCHEMBL10798317 0.92 MAPK1 (0.50) MAPK1MAPTHSD17B10POLBCDK1
SCHEMBL11803039 0.88 MAPK1 (0.47) MAPK1MAPTPOLBCA9CA1
SCHEMBL2605174 0.88 MAPK1 (0.47) MAPK1MAPTHSD17B10POLBCDK1
SCHEMBL4115128 0.88 MAPT (0.47) MAPK1MAPTHSD17B10CA12CA9
SCHEMBL4111687 0.88 MAPK1 (0.47) MAPK1MAPTPOLBCA9CA1
SCHEMBL11132586 0.88 MAPK1 (0.47) MAPK1MAPTHSD17B10POLBCDK1
SCHEMBL154305 0.88 MAPT (0.47) MAPK1MAPTHSD17B10POLBCDK1
SCHEMBL21875991 0.88 MAPK1 (0.47) MAPK1MAPTHSD17B10POLBCDK1
SCHEMBL2115403 0.88 MAPK1 (0.47) MAPK1MAPTHSD17B10POLBCDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 53189 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
EP-4049841-B1 HYBRID RESIN COMPOSITION CUBICURE GMBH (AT) 2026-03-18 EP claimed
US-12577415-B2 Associative rheology modifier composition and methods for making thereof Kraton Corporation (US) 2026-03-17 US claimed
CN-121574667-A Composite adhesive film and preparation method and application thereof 杭州福斯特应用材料股份有限公司 2026-02-27 CN claimed
US-12551434-B2 Zwitterionic polymer particle compositions and related methods WAYNE STATE UNIVERSITY (US) 2026-02-17 US claimed
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-20250388744-A1 HALOGEN FREE AND PHOSPHORUS FREE LOW LOSS FLAME RETARDANT COMPOSITIONS CONTAINING POLYCYCLIC-OLEFINIC POLYMER WITH OLEFINIC AND ANHYDRIDE FUNCTIONALITY AND MELAMINE PROMERUS, LLC (US) 2025-12-25 US claimed
WO-2025238104-A1 RESIN COMPOSITION FOR A RADIATION-CURING ADDITIVE MANUFACTURING PROCESS, PARTICULARLY FOR A LITHOGRAPHIC MANUFACTURING PROCESS ALIGN TECHNOLOGY, INC. (US) 2025-11-20 WO claimed
US-20250353962-A1 PHOTOPOLYMERIZABLE THERMOPLASTICS AND METHODS OF MAKING AND USING SAME UNIV COLORADO REGENTS (US) 2025-11-20 US claimed
EP-4650397-A1 RESIN COMPOSITION FOR A RADIATION-CURABLE ADDITIVE MANUFACTURING PROCESS Cubicure GmbH (AT) 2025-11-19 EP claimed
US-3957916-A CROSSLINKED GRAFT COPOLYMER OF AN ACRYLIC ESTER HITACHI, LTD. (JA) 1976-05-18 US claimed
US-3957699-A Process for polymerizing allylamines employing a redox initiator consisting of Fe++ or Ti+++ with H2 O2, hydroxyl amine, or hydroperoxides to form insoluble crosslinked polymers ICI AUSTRALIA LIMITED (AU) 1976-05-18 US claimed
US-3950287-A CURING, AMINES, FREE RADICAL CATALYSTS ASHLAND OIL, INC. (US) 1976-04-13 US claimed
US-3948796-A Triallyl cyanurate with high ringbound chlorine content AMERICAN CYANAMID COMPANY (US) 1976-04-06 US claimed
US-3947525-A ETHYLENE-CHLOROTRIFLUOROETHYLENE COPOLYMER ALLIED CHEMICAL CORPORATION (US) 1976-03-30 US claimed
US-3945966-A SEALS, GASKETS, O-RINGS, THERMOSTABILITY HORIZONS INCORPORATED A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1976-03-23 US claimed
US-3937756-A FIRE RETARDANT POLYESTER RESINS JEFFERSON CHEMICAL COMPANY, INC. (US) 1976-02-10 US claimed
US-3936441-A Process for the production of water adsorbing but water-insoluble cellulose ethers HOECHST AKTIENGESELLSCHAFT (DT) 1976-02-03 US claimed
US-3936414-A UNSATURATED MONOMER AND POLYMER, POLYPHENYLENE ETHER, PEROXIDE CATALYST FMC CORPORATION (US) 1976-02-03 US claimed
US-3932321-A HOMO- AND COPOLYMERS OF HALOPHENYL ACRYLATES JAPAN SYNTHETIC RUBBER COMPANY LIMITED (JA) 1976-01-13 US claimed