SCHEMBL154305

SCHEMBL154305

C=CCOc1nc(O)nc(OCC=C)n1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
MAPK1 P28482 3/20 0.47
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
MGMT P16455 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CCNA1 P78396 1/20 0.31
HSD17B10 Q99714 2/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL336841 0.95 MAPT (0.47) MAPTMAPK1CDK1CCNB1MGMT
SCHEMBL14410167 0.90 MAPT (0.41) MAPTMAPK1HSD17B10HPGDSMN1; SMN2
SCHEMBL1195297 0.89 MAPT (0.40) MAPTMAPK1
SCHEMBL23181 0.88 MAPK1 (0.55) MAPTMAPK1CDK1CCNB1MGMT
SCHEMBL24728020 0.86 MAPT (0.41) MAPTMAPK1
Hydrogen Sulfide SCHEMBL20395887 0.85 MAPK1 (0.53) MAPTMAPK1CDK1CCNB1MGMT
SCHEMBL11207182 0.83 ALDH1A1 (0.47) MAPTMAPK1HPGDTSHRMEN1
SCHEMBL24141678 0.83 MAPT (0.36) MAPTMAPK1
SCHEMBL10798317 0.81 MAPK1 (0.50) MAPTMAPK1CDK1CCNB1MGMT
Acetone SCHEMBL11807912 0.80 MAPT (0.46) MAPTMAPK1TSHRLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4377373-A1 CURABLE, ONE-PART, DUAL-STAGE THIOL-ENE-EPOXY LIQUID ADHESIVES AND METHODS 3M Innovative Properties Company (US) 2024-06-05 EP claimed
CN-117813335-A Curable one-part two-stage thiol-ene-epoxy liquid adhesives and methods 3M创新有限公司 2024-04-02 CN claimed
WO-2023007439-A1 CURABLE, ONE-PART, DUAL-STAGE THIOL-ENE-EPOXY LIQUID ADHESIVES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-02-02 WO claimed
CN-113278234-B Low-smoke low-halogen flame-retardant PVC cable material and preparation method thereof 江苏宝源高新电工有限公司 2022-08-12 CN claimed
CN-113278234-A Low-smoke low-halogen flame-retardant PVC cable material and preparation method thereof 江苏宝源高新电工有限公司 2021-08-20 CN claimed
US-8188164-B2 Cellulose-based masterbatch with improved breaking elongation, application thereof and method for preparing the same TAIWAN TEXTILE RESEARCH INSTITUTE (TW) 2012-05-29 US claimed
US-20110245447-A1 Cellulose-Based Masterbatch with Networked Structure, Application Thereof and Method for Preparing the Same TAIWAN TEXTILE RESEARCH INSTITUTE (TW) 2011-10-06 US claimed
US-20110237708-A1 Cellulose-Based Masterbatch with Improved Breaking Elongation, Application Thereof and Method for Preparing the Same TAIWAN TEXTILE RESEARCH INSTITUTE (TW) 2011-09-29 US claimed
EP-2368915-A1 Cellulose-based masterbatch with improved breaking elongation, application thereof and method for preparing the same Taiwan Textile Research Institute (CN) 2011-09-28 EP claimed
EP-0803529-A1 Curable resin composition NIPPON PAINT CO., LTD. (JP) 1997-10-29 EP claimed
EP-0065477-B1 COMPOSITE OF RUBBER AND METAL REINFORCEMENT THEREFOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-07-23 EP claimed
US-4391318-A CONTAINS CYANURIC DERIVATIVE, FOR TIRES, BELTS AND HOSES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-07-05 US claimed
EP-0019113-B1 AROMATIC POLYAMIDE PAPER-LIKE SHEET AND PROCESSES FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-04-13 EP claimed
EP-0065477-A1 Composite of rubber and metal reinforcement therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-11-24 EP claimed
US-4256558-A EXTRUSION OF A BLEND OF POLYETHYLENE TEREPHTHALATE AND A DIALLYL COMPOUND FOLLOWED BY RADIATION CURING; FILMS AND FILAMENTS HAVING GOOD HEAT RESISTANCE AND PHOTOSTABILITY TEIJIN LIMITED (JP) 1981-03-17 US claimed
US-4085162-A FIREPROOFING, DIELECTRICS GENERAL ELECTRIC COMPANY (US) 1978-04-18 US claimed
US-3965054-A Foamable polyolefin composition and method for manufacturing foamed polyolefin THE FURUKAWA ELECTRIC CO., LTD. (JA) 1976-06-22 US claimed
US-3960988-A FREE RADICALS POLYSAR LIMITED (CA) 1976-06-01 US claimed
JP-56045940-A None JP disclosed
US-3948960-A ADDITION, HYDROGEN PEROXIDE, INTRAPHASE PONY INDUSTRIES, INC., A CORP. OF DE 1976-04-06 US disclosed