SCHEMBL10798317

SCHEMBL10798317

C=CCOc1nc(OCC=C)nc(OCCOc2nc(OCC=C)nc(OCC=C)n2)n1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.50
MAPT P10636 1/20 0.50
CDK1 P06493 1/20 0.33
CCNB1 P14635 1/20 0.33
MGMT P16455 1/20 0.33
CCNA2 P20248 1/20 0.33
CDK2 P24941 1/20 0.33
CCNA1 P78396 1/20 0.33
POLB P06746 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CA12 O43570 4/20 0.31
CA9 Q16790 4/20 0.31
CA1 P00915 3/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10960929 0.93 MAPT (0.46) MAPK1MAPTCDK1CCNB1MGMT
SCHEMBL23181 0.92 MAPK1 (0.55) MAPK1MAPTCDK1CCNB1MGMT
SCHEMBL10815003 0.91 MAPT (0.47) MAPK1MAPTCDK1CCNB1MGMT
Hydrogen Sulfide SCHEMBL20395887 0.90 MAPK1 (0.53) MAPK1MAPTCDK1CCNB1MGMT
SCHEMBL11182506 0.89 MAPT (0.46) MAPK1MAPTCDK1CCNB1MGMT
SCHEMBL10961266 0.89 MAPT (0.46) MAPK1MAPTCDK1CCNB1MGMT
SCHEMBL1065177 0.89 MAPT (0.46) MAPK1MAPTCDK1CCNB1MGMT
SCHEMBL10804391 0.87 MAPT (0.44) MAPK1MAPT
SCHEMBL9501074 0.87 MAPT (0.44) MAPK1MAPT
SCHEMBL6124831 0.87 MAPT (0.44) MAPK1MAPTPOLBHSD17B10CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0019113-B1 AROMATIC POLYAMIDE PAPER-LIKE SHEET AND PROCESSES FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-04-13 EP claimed
EP-0091778-B1 IMPROVEMENT IN OR RELATING TO AROMATIC POLYAMIDE FILM TEIJIN LIMITED (JP) 1987-12-09 EP disclosed
US-4539393-A Dimensionally stable poly-m-phenylene isophthalamide film TEIJIN LIMITED (JP) 1985-09-03 US disclosed
US-4498957-A Aromatic polyamide paper-like sheet and processes for producing the same TEIJIN LIMITED (JP) 1985-02-12 US disclosed
EP-0091778-A2 Improvement in or relating to aromatic polyamide film TEIJIN LIMITED (JP) 1983-10-19 EP disclosed
EP-0019113-B1 AROMATIC POLYAMIDE PAPER-LIKE SHEET AND PROCESSES FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-04-13 EP disclosed
EP-0007114-B1 AROMATIC POLYAMIDE FILM AND PROCESS FOR PRODUCING THE SAME TEIJIN LIMITED (JP) 1983-03-16 EP disclosed
EP-0046954-A2 Shaped article of aromatic polyamide TEIJIN LIMITED (JP) 1982-03-10 EP disclosed
US-4291142-A Crosslinked aromatic polyamide film and process for producing the same TEIJIN, LIMITED (JP) 1981-09-22 US disclosed
EP-0019113-A1 Aromatic polyamide paper-like sheet and processes for producing the same TEIJIN LIMITED (JP) 1980-11-26 EP disclosed
EP-0007114-A1 Aromatic polyamide film and process for producing the same TEIJIN LIMITED (JP) 1980-01-23 EP disclosed