Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 20/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 16/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21719066 | 0.82 | KIF11 (0.32) | — | |
| SCHEMBL24609350 | 0.77 | CYP11B2 (0.42) | CYP11B2CYP11B1CYP19A1CYP2C9 | |
| SCHEMBL7939338 | 0.76 | CYP11B2 (0.46) | CYP11B2CYP11B1CYP19A1CYP2C9 | |
| SCHEMBL746198 | 0.74 | POLB (0.41) | CYP11B2CYP11B1CYP19A1CYP2C9 | |
| SCHEMBL21697681 | 0.74 | CYP11B2 (0.50) | CYP11B2CYP11B1CYP19A1CYP2C9 | |
| SCHEMBL30581493 | 0.74 | CYP11B2 (0.48) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL7878737 | 0.74 | CYP11B2 (0.41) | CYP11B2CYP11B1CYP19A1CYP2C9 | |
| SCHEMBL30314158 | 0.73 | CYP11B1 (0.38) | CYP11B2CYP11B1CYP19A1CYP2C9 | |
| SCHEMBL5700171 | 0.73 | CYP11B1 (0.38) | CYP11B2CYP11B1CYP19A1CYP2C9 | |
| SCHEMBL2560130 | 0.71 | CYP11B2 (0.39) | CYP11B2CYP11B1CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057975-A1 | MUTANT IDH2 INHIBITOR AND APPLICATION THEREOF | 贝达药业股份有限公司 | 2021-04-01 | — | — | WO | disclosed |