SCHEMBL231827

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3073519	1.00	ESR1 (0.52)	ESR1GAATSHRACHEACP3
	SCHEMBL342736	1.00	ESR1 (0.52)	ESR1GAATSHRACHEACP3
	SCHEMBL13993318	0.86	ESR1 (0.59)	ESR1GAATSHRACHEACP3
	SCHEMBL30507724	0.83	ESR1 (0.56)	ESR1GAATSHRACHEACP3
	SCHEMBL5101317	0.83	GABRA1 (0.50)	TSHRGABRA1GABRB2SLC6A2CYP3A4
	SCHEMBL5101318	0.83	GABRA1 (0.50)	TSHRGABRA1GABRB2SLC6A2CYP3A4
	SCHEMBL382010	0.83	GABRA1 (0.50)	TSHRGABRA1GABRB2SLC6A2CYP3A4
	SCHEMBL14040083	0.82	ESR1 (0.50)	ESR1GAATSHRACHEACP3
	SCHEMBL17446315	0.82	ESR1 (0.50)	ESR1GAATSHRACHEACP3
	SCHEMBL6055139	0.82	ESR1 (0.50)	ESR1GAATSHRACHEACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 597 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.