Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | LTA4H | P09960 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12432840 | 1.00 | HTR7 (0.35) | HTR7DRD2HTR1AHTR6DRD3 | |
| SCHEMBL2314376 | 0.98 | HTR7 (0.35) | HTR7DRD2HTR1AHTR6DRD3 | |
| SCHEMBL12432708 | 0.98 | HTR7 (0.35) | HTR7DRD2HTR1AHTR6DRD3 | |
| SCHEMBL12432614 | 0.95 | DRD2 (0.34) | HTR7DRD2HTR1AHTR6DRD3 | |
| SCHEMBL2315661 | 0.95 | DRD2 (0.34) | HTR7DRD2HTR1AHTR6DRD3 | |
| SCHEMBL14135130 | 0.95 | HTR7 (0.35) | HTR7DRD2HTR1AHTR6DRD3 | |
| SCHEMBL12433995 | 0.95 | HTR7 (0.35) | HTR7DRD2HTR1AHTR6DRD3 | |
| SCHEMBL2317089 | 0.95 | HTR7 (0.35) | HTR7DRD2HTR1AHTR6DRD3 | |
| SCHEMBL12433996 | 0.94 | DRD2 (0.35) | HTR7DRD2HTR1AHTR6DRD3 | |
| SCHEMBL2314393 | 0.92 | MAOB (0.39) | DRD2DRD3LTA4HMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125782-B1 | ARYL CARBOXYLIC ACID CYCLOHEXYL AMIDE DERIVATIVES | NOVARTIS AG (CH) | 2011-08-03 | — | — | EP | disclosed |