SCHEMBL231857

SCHEMBL231857

CC[C@H](C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 8/20 0.64
FAP Q12884 2/20 0.64
DPP8 Q6V1X1 2/20 0.64
DPP9 Q86TI2 2/20 0.64
DPP7 Q9UHL4 2/20 0.64
ACE P12821 6/20 0.58
REN P00797 3/20 0.58
KDM4E B2RXH2 1/20 0.58
F2 P00734 1/20 0.58
LMNA P02545 1/20 0.58
LTA4H P09960 1/20 0.58
MAPT P10636 1/20 0.58
PEPD P12955 1/20 0.58
ALOX15 P16050 1/20 0.58
PTGS1 P23219 1/20 0.58
HTR2A P28223 1/20 0.58
PTGS2 P35354 1/20 0.58
HRH1 P35367 1/20 0.58
THPO P40225 1/20 0.58
PMP22 Q01453 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30729262 1.00 DPP4 (0.64) DPP4FAPDPP8DPP9DPP7
SCHEMBL30729240 1.00 DPP4 (0.64) DPP4FAPDPP8DPP9DPP7
SCHEMBL22498704 1.00 DPP4 (0.64) DPP4FAPDPP8DPP9DPP7
SCHEMBL231856 1.00 DPP4 (0.64) DPP4FAPDPP8DPP9DPP7
SCHEMBL30179346 1.00 DPP4 (0.64) DPP4FAPDPP8DPP9DPP7
SCHEMBL7405423 1.00 DPP4 (0.64) DPP4FAPDPP8DPP9DPP7
SCHEMBL5278976 1.00 DPP4 (0.64) DPP4FAPDPP8DPP9DPP7
SCHEMBL25276458 0.95 DPP4 (0.59) DPP4FAPDPP8DPP9DPP7
SCHEMBL1646849 0.95 DPP4 (0.59) DPP4FAPDPP8DPP9DPP7
SCHEMBL1646847 0.95 DPP4 (0.59) DPP4FAPDPP8DPP9DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118984702-A Topical preparation for treating or preventing dry skin itch MC2疗法有限公司 2024-11-19 CN claimed
CN-118843470-A Composition for metabolic health 国际营养与健康丹麦有限公司 2024-10-25 CN claimed
US-20240315296-A1 PEPTIDE COMPOUNDS FOR FLAVOR MODULATING CJ CHEILJEDANG CORPORATION (KR) 2024-09-26 US claimed
CN-118496322-A Polypeptide inhibitor for targeted degradation of beta-catenin and application thereof 昆明医科大学 2024-08-16 CN claimed
EP-4364582-A1 PEPTIDE COMPOUNDS FOR FLAVOR MODULATING CJ Cheiljedang Corporation (KR) 2024-05-08 EP claimed
CN-117838878-A Antibody-STING agonist conjugates and their use in immunotherapy 免疫传感器治疗股份有限公司 2024-04-09 CN claimed
CN-117677302-A Peptide compounds for flavor modulation CJ第一制糖株式会社 2024-03-08 CN claimed
US-20240059740-A1 CYCLIC PEPTIDES AND USES THEREOF PreveCeutical Medical Inc. (CA) 2024-02-22 US claimed
CN-117106028-B Protease activated peptide and application thereof in preparation of medicines for preventing and/or treating myocardial ischemia/reperfusion injury 首都医科大学附属北京朝阳医院 2024-02-13 CN claimed
US-20230414699-A1 TREATMENT OF DERMATOLOGICAL CONDITIONS MC2 THERAPEUTICS LTD (GB) 2023-12-28 US claimed
US-20220257789-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS EXELIXIS, INC. 2022-08-18 US claimed
WO-2022133540-A1 CYCLIC PEPTIDES AND USES THEREOF PreveCeutical Medical Inc. (CA) 2022-06-30 WO claimed
EP-3999118-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY Immunesensor Therapeutics, Inc. (US) 2022-05-25 EP claimed
EP-3994150-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS Iconic Therapeutics, Inc. (US) 2022-05-11 EP claimed
WO-2022074228-A1 TREATMENT OF DERMATOLOGICAL CONDITIONS MC2 THERAPEUTICS LTD (GB) 2022-04-14 WO claimed
CN-114222752-A Anti-tissue factor antibody-drug conjugates and related methods 伊科尼克治疗公司 2022-03-22 CN claimed
US-20150065366-A1 Biomarkers for Bladder Cancer and Methods Using the Same METABOLON, INC. 2015-03-05 US claimed
CN-104204798-A Biomarkers for bladder cancer and methods using the same METABOLON INC 2014-12-10 CN claimed
EP-2776832-A1 BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME Metabolon, Inc. (US) 2014-09-17 EP claimed
WO-2013070839-A1 BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME METABOLON, INC. (US) 2013-05-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059740-A1 CYCLIC PEPTIDES AND USES THEREOF VIP, NGLY1, LNPEP DPP4 1370/4885FAP 369/4885DPP8 1017/4885
US-20220257789-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS F3, F13B, TFPI DPP4 982/4885FAP 598/4885DPP8 841/4885
US-20230414699-A1 TREATMENT OF DERMATOLOGICAL CONDITIONS PRKDC, DPM1, MMP8 DPP4 487/4885FAP 291/4885DPP8 600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.