Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25480858 | 1.00 | ACACB (0.39) | ACACBKMT2AEPHX1HPGDANPEP | |
| SCHEMBL10199651 | 0.83 | KMT2A (0.45) | ACACBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL23553955 | 0.79 | KMT2A (0.39) | ACACBKMT2AEPHX1HPGDLTA4H | |
| SCHEMBL6136421 | 0.78 | SMN1; SMN2 (0.49) | ACACBEPHX1LTA4HRAB9A | |
| SCHEMBL4424684 | 0.78 | SMN1; SMN2 (0.49) | ACACBEPHX1LTA4HRAB9A | |
| SCHEMBL7882899 | 0.77 | KMT2A (0.53) | KMT2AEPHX1HPGDEPHX2NPC1 | |
| SCHEMBL23553285 | 0.76 | KMT2A (0.40) | ACACBKMT2AEPHX1HPGDEPHX2 | |
| SCHEMBL27495741 | 0.76 | ACACB (0.40) | ACACBKMT2AEPHX1HPGDGLS | |
| SCHEMBL7437533 | 0.75 | HPGD (0.57) | KMT2AEPHX1HPGDLTA4HEPHX2 | |
| SCHEMBL4412011 | 0.75 | TSHR (0.45) | ACACBKMT2AEPHX1HPGDEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210101886-A1 | IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. | 2021-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101886-A1 | IL-17A MODULATORS AND USES THEREOF | IL17A, IL2, IL36G | ACACB 1975/4885KMT2A 4100/4885EPHX1 2501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.