Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15964570 | 0.90 | BLM (0.31) | BLMMEN1GRIN2DLMNACYP3A4 | |
| SCHEMBL23189099 | 0.85 | — | — | |
| SCHEMBL15964573 | 0.83 | BLM (0.32) | BLMMEN1GRIN2DLMNACYP3A4 | |
| SCHEMBL23188855 | 0.80 | BLM (0.32) | BLMMEN1GRIN2DLMNACYP3A4 | |
| SCHEMBL15964641 | 0.79 | TGM2 (0.36) | BLMMEN1GRIN2DLMNACYP3A4 | |
| SCHEMBL30587582 | 0.79 | TGM2 (0.36) | BLMMEN1GRIN2DLMNACYP3A4 | |
| SCHEMBL28719592 | 0.79 | TGM2 (0.36) | BLMMEN1GRIN2DLMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL30092725 | 0.78 | TGM2 (0.35) | BLMMEN1GRIN2DLMNACYP3A4 | |
| SCHEMBL23188854 | 0.77 | ALDH1A1 (0.38) | BLMMEN1GRIN2DLMNACYP3A4 | |
| SCHEMBL31663492 | 0.74 | CYP19A1 (0.38) | BLMMEN1GRIN2DLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2021-04-07 | — | — | EP | disclosed |