Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 7/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15964660 | 0.82 | HTR2C (0.34) | SRD5A1HTR2C | |
| SCHEMBL23189195 | 0.82 | RIPK1 (0.35) | SRD5A1 | |
| SCHEMBL15964662 | 0.73 | AHR (0.50) | SRD5A1HTR2C | |
| SCHEMBL23189074 | 0.73 | TP53 (0.32) | ALDH1A1TP53ALOX15HSD17B10 | |
| SCHEMBL23189097 | 0.72 | CES1 (0.44) | CES1SRD5A1ALDH1A1MAPTTP53 | |
| SCHEMBL15964661 | 0.71 | DDB1 (0.31) | — | |
| SCHEMBL9405624 | 0.70 | AHR (0.50) | SRD5A1HTR2CTP53 | |
| SCHEMBL15964668 | 0.70 | RIPK1 (0.41) | — | |
| SCHEMBL5357730 | 0.69 | GRIA1 (0.49) | CES1MAPTTP53TDP1 | |
| SCHEMBL18743979 | 0.67 | HTR5A (0.40) | SRD5A1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508484-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2021-04-07 | — | — | EP | disclosed |