Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2321459 | 0.93 | LPAR3 (0.48) | TYMSGRM4LPAR3LPAR2BBOX1 | |
| SCHEMBL19212082 | 0.85 | GRM4 (0.58) | TYMSGRM4LPAR3LPAR2BBOX1 | |
| SCHEMBL6678291 | 0.80 | TYMS (0.55) | TYMSGRM4LPAR3LPAR2BBOX1 | |
| SCHEMBL6940143 | 0.78 | LPAR3 (0.40) | TYMSGRM4LPAR3LPAR2 | |
| SCHEMBL17915728 | 0.76 | FDPS (0.58) | LMNACYP3A4NFKB1BLMPMP22 | |
| SCHEMBL5697415 | 0.76 | FDPS (0.61) | LPAR3LPAR2 | |
| SCHEMBL2318641 | 0.75 | TYMS (0.55) | TYMSGRM4LPAR3LPAR2BBOX1 | |
| SCHEMBL10764074 | 0.75 | TYMS (0.55) | TYMSGRM4LPAR3LPAR2BBOX1 | |
| SCHEMBL27769762 | 0.74 | GGPS1 (0.65) | LPAR3LPAR2 | |
| SCHEMBL4413277 | 0.73 | TYMS (0.52) | TYMSGRM4LPAR3LPAR2BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3413934-B1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2021-10-13 | — | — | EP | claimed |
| CN-109195641-B | Improved implant treatment with phosphonic acid compounds | 纳米桥接分子股份公司 | 2021-07-27 | — | — | CN | claimed |
| US-11000627-B2 | Treatment of implants with phosphonic acid compounds | NANO BRIDGING MOLECULES SA (CH) | 2021-05-11 | — | — | US | claimed |
| EP-1698357-B1 | POLYPHOSPHONIC ACIDS AND DERIVATIVES THEREOF | UNIV GENEVE (CH) | 2019-06-26 | — | — | EP | claimed |
| US-20190038802-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2019-02-07 | — | — | US | claimed |
| EP-3413934-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | Nano Bridging Molecules SA (CH) | 2018-12-19 | — | — | EP | claimed |
| WO-2017137623-A1 | IMPROVED TREATMENT OF IMPLANTS WITH PHOSPHONIC ACID COMPOUNDS | NANO BRIDGING MOLECULES SA (CH) | 2017-08-17 | — | — | WO | claimed |
| US-9730795-B2 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2017-08-15 | — | — | US | claimed |
| EP-1351722-B2 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2016-02-17 | — | — | EP | claimed |
| US-20140316533-A1 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2014-10-23 | — | — | US | claimed |
| US-7090496-B2 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2006-08-15 | — | — | US | claimed |
| EP-1351722-B1 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2006-07-05 | — | — | EP | claimed |
| EP-1343545-B1 | ENDOSSEOUS IMPLANT | UNIV GENEVE (CH) | 2006-07-05 | — | — | EP | claimed |
| US-20040054422-A1 | Endosseous implant | UNIVERSITE DE GENEVE (CH) | 2004-03-18 | — | — | US | claimed |
| US-20040049287-A1 | Surface treated with a phosphonic acid, ester, amide or salt; orthopaedic prostheses; bone replacements or reinforcements, dentistry | UNIVERSITE DE GENEVE (CH) | 2004-03-11 | — | — | US | claimed |
| EP-1351722-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2003-10-15 | — | — | EP | claimed |
| EP-1343545-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2003-09-17 | — | — | EP | claimed |
| WO-2002040073-A1 | ENDOSSEOUS IMPLANT | UNIVERSITÉ DE GENÈVE (CH) | 2002-05-23 | — | — | WO | claimed |
| WO-2002040075-A1 | ENDOSSEOUS IMPLANT | UNIVERSITÉ DE GENÈVE (CH) | 2002-05-23 | — | — | WO | claimed |
| WO-2002040074-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2002-05-23 | — | — | WO | claimed |