Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2319103 | 0.78 | TYMS (0.50) | LPAR3LPAR2GRM4TYMS | |
| SCHEMBL7153762 | 0.74 | GGPS1 (0.49) | LPAR3LPAR2TYMSS1PR1S1PR3 | |
| SCHEMBL2321459 | 0.73 | LPAR3 (0.48) | LPAR3LPAR2GRM4TYMSGGPS1 | |
| SCHEMBL6840323 | 0.70 | LPAR3 (0.40) | LPAR3LPAR2LPAR1GGPS1FDPS | |
| SCHEMBL18631699 | 0.70 | LPAR3 (0.50) | LPAR3LPAR2TYMSS1PR1S1PR3 | |
| SCHEMBL12806713 | 0.69 | LPAR3 (0.39) | LPAR3LPAR2LPAR1GGPS1FDPS | |
| SCHEMBL6940142 | 0.68 | CYP3A4 (0.32) | — | |
| SCHEMBL899554 | 0.67 | LPAR3 (0.47) | LPAR3LPAR2TYMSS1PR1S1PR3 | |
| SCHEMBL5697415 | 0.67 | FDPS (0.61) | LPAR3LPAR2LPAR1GGPS1FDPS | |
| SCHEMBL9504088 | 0.67 | LPAR3 (0.62) | LPAR3LPAR2TYMSS1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351722-A1 | ENDOSSEOUS IMPLANT | UNIVERSITE DE GENEVE (CH) | 2003-10-15 | — | — | EP | claimed |
| WO-2002040075-A1 | ENDOSSEOUS IMPLANT | UNIVERSITÉ DE GENÈVE (CH) | 2002-05-23 | — | — | WO | claimed |