Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519104 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5527291 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5520084 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5525101 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5511001 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL14823816 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL293980 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5515422 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL14823812 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL21441786 | 0.97 | HDAC8 (0.58) | HDAC8HDAC6EPHX1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017567-A1 | METHODS OF GENERATING NANOARRAYS AND MICROARRAYS | NAUTILUS SUBSIDIARY, INC. | 2022-01-20 | — | — | US | disclosed |
| US-11203612-B2 | Methods of generating nanoarrays and microarrays | NAUTILUS BIOTECHNOLOGY, INC. (US) | 2021-12-21 | — | — | US | disclosed |
| US-20210101930-A1 | METHODS OF GENERATING NANOARRAYS AND MICROARRAYS | NAUTILUS BIOTECHNOLOGY, INC. | 2021-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101930-A1 | METHODS OF GENERATING NANOARRAYS AND MICROARRAYS | NAPA, SSBP1, NASP | HDAC8 3234/4885HDAC6 1925/4885EPHX1 4457/4885 |
| US-11203612-B2 | Methods of generating nanoarrays and microarrays | NAPA, SSBP1, NASP | HDAC8 3234/4885HDAC6 1925/4885EPHX1 4457/4885 |
| US-20220017567-A1 | METHODS OF GENERATING NANOARRAYS AND MICROARRAYS | NAPA, SSBP1, NASP | HDAC8 3234/4885HDAC6 1925/4885EPHX1 4457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.