Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519104 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5527291 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5520084 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5511001 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL14823816 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL23192018 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL293980 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5515422 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL14823812 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL21441786 | 0.97 | HDAC8 (0.58) | HDAC8HDAC6EPHX1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3698699-B2 | — | — | 2005-09-21 | — | — | JP | claimed |
| US-20040106724-A1 | Natural rubber produced from latex and composition comprising the same | BRIDGESTONE CORPORATION (JP) | 2004-06-03 | — | — | US | claimed |
| JP-2004514009-A | — | — | 2004-05-13 | — | — | JP | claimed |
| EP-1332161-A2 | DRYING PROCESSES FOR NATURAL RUBBER, STABILIZED NR COMPOSITIONS | Bridgestone Corporation (JP) | 2003-08-06 | — | — | EP | claimed |
| US-6531527-B2 | Liquid dilution after coagulation | BRIDGESTONE CORPORATION (JP) | 2003-03-11 | — | — | US | claimed |
| WO-2002038667-A2 | NATURAL RUBBER PRODUCED FROM LATEX AND COMPOSITION COMPRISING THE SAME | BRIDGESTONE CORPORATION (JP) | 2002-05-16 | — | — | WO | claimed |
| US-20020035195-A1 | Viscosity-stabilizer-containing natural rubber latex and natural rubber and a production process thereof | BRIDGESTONE CORPORATION | 2002-03-21 | — | — | US | claimed |
| US-11129790-B2 | Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates | NORTHEASTERN UNIVERSITY (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200385583-A1 | POLYMERIC FLUOROPHORES, COMPOSITIONS COMPRISING THE SAME, AND METHODS OF PREPARING AND USING THE SAME | UNITED STATES DEPARTMENT OF ENERGY | 2020-12-10 | — | — | US | disclosed |
| EP-2957587-B1 | METHOD FOR PRODUCING RUBBER COMPOSITION, AND RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2018-12-26 | — | — | EP | disclosed |
| US-10087292-B2 | Method for producing rubber composition, and rubber composition | BRIDGESTONE CORPORATION (JP) | 2018-10-02 | — | — | US | disclosed |
| EP-3196232-B1 | METHOD FOR MANUFACTURING RUBBER COMPOSITION, AND RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2018-07-04 | — | — | EP | disclosed |
| CN-105073844-B | The manufacture method and rubber composition of rubber composition | 株式会社普利司通 | 2018-04-06 | — | — | CN | disclosed |
| EP-1332161-A2 | DRYING PROCESSES FOR NATURAL RUBBER, STABILIZED NR COMPOSITIONS | Bridgestone Corporation (JP) | 2003-08-06 | — | — | EP | disclosed |
| US-6531527-B2 | Liquid dilution after coagulation | BRIDGESTONE CORPORATION (JP) | 2003-03-11 | — | — | US | disclosed |
| WO-2002038667-A2 | NATURAL RUBBER PRODUCED FROM LATEX AND COMPOSITION COMPRISING THE SAME | BRIDGESTONE CORPORATION (JP) | 2002-05-16 | — | — | WO | disclosed |
| US-20020035195-A1 | Viscosity-stabilizer-containing natural rubber latex and natural rubber and a production process thereof | BRIDGESTONE CORPORATION | 2002-03-21 | — | — | US | disclosed |
| EP-0613924-B1 | Method of production of natural rubber treated with viscosity stabilizers | BRIDGESTONE CORP (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5710200-A | DRYING NATURAL RUBBER AND REACTING RUBBER WITH A HYDRAZIDE VISCOSITY STABILIZER | BRIDGESTONE CORPORATION (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0613924-A1 | Natural rubber treated with viscosity stabilizers and production thereof | BRIDGESTONE CORPORATION (JP) | 1994-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129790-B2 | Chemo-enzymatic site-specific modification of peptides and proteins to form cleavable conjugates | GLUL, QPCT, DNPEP | HDAC8 2376/4885HDAC6 3082/4885EPHX1 2249/4885 |
| US-20200385583-A1 | POLYMERIC FLUOROPHORES, COMPOSITIONS COMPRISING THE SAME, AND METHODS OF PREPARING AND USING THE SAME | CLTB, PAICS, HLCS | HDAC8 3097/4885HDAC6 986/4885EPHX1 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.