Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519104 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5527291 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5520084 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5525101 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5511001 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL14823816 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL23192018 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL5515422 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL14823812 | 1.00 | HDAC8 (0.61) | HDAC8HDAC6EPHX1CES2CES1 | |
| SCHEMBL21441786 | 0.97 | HDAC8 (0.58) | HDAC8HDAC6EPHX1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12071503-B2 | Method for preparing and repairing covalent organic framework materials | ZHEJIANG UNIVERSITY (CN) | 2024-08-27 | — | — | US | claimed |
| CN-115487866-B | Covalent organic framework material coupling nano metal catalyst and preparation method thereof | 浙江大学 | 2024-05-14 | — | — | CN | claimed |
| CN-115487866-A | Covalent organic framework material coupled nano metal catalyst and preparation method thereof | 浙江大学 | 2022-12-20 | — | — | CN | claimed |
| CN-114685933-A | Polyformaldehyde composite material and preparation method and application thereof | 江苏金发科技新材料有限公司 | 2022-07-01 | — | — | CN | claimed |
| US-20220153904-A1 | A METHOD FOR PREPARING AND REPAIRING COVALENT ORGANIC FRAMEWORK MATERIALS | ZHEJIANG UNIVERSITY (CN) | 2022-05-19 | — | — | US | claimed |
| CN-113562855-A | Environment-friendly efficient boiler water regulator for drum boiler | 浙江砉润科技有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-109957209-B | Epoxy resin composition, resin product, preparation method thereof and resin product | 北京科化新材料科技有限公司 | 2021-08-17 | — | — | CN | claimed |
| EP-3862341-A1 | METHOD FOR PREPARING AND METHOD FOR REPAIRING DEFECTS OF COVALENT ORGANIC FRAMEWORK MATERIAL | Zhejiang University (CN) | 2021-08-11 | — | — | EP | claimed |
| CN-112654599-A | Preparation method and defect repair method of covalent organic framework material | 浙江大学 | 2021-04-13 | — | — | CN | claimed |
| CN-110523354-B | Preparation method of microreactor containing immobilized catalyst | 浙江大学 | 2021-01-19 | — | — | CN | claimed |
| US-20040106724-A1 | Natural rubber produced from latex and composition comprising the same | BRIDGESTONE CORPORATION (JP) | 2004-06-03 | — | — | US | claimed |
| JP-2004514009-A | — | — | 2004-05-13 | — | — | JP | claimed |
| US-20040006042-A1 | Diaminopyrimidines and combination therapies effective for treatment of P-glycoprotein positive cancers | BERRY DAVID ALLEN (US) | 2004-01-08 | — | — | US | claimed |
| EP-1332161-A2 | DRYING PROCESSES FOR NATURAL RUBBER, STABILIZED NR COMPOSITIONS | Bridgestone Corporation (JP) | 2003-08-06 | — | — | EP | claimed |
| CN-1411472-A | Natural rubber produced from latex and composition comprising same | BRIDGESTONE CORP (JP) | 2003-04-16 | — | — | CN | claimed |
| US-6531527-B2 | Liquid dilution after coagulation | BRIDGESTONE CORPORATION (JP) | 2003-03-11 | — | — | US | claimed |
| US-20030044360-A1 | Process and composition for high efficacy teeth whitening | SCIENTIFIC PHARMACEUTICALS, INC. | 2003-03-06 | — | — | US | claimed |
| WO-2002038667-A2 | NATURAL RUBBER PRODUCED FROM LATEX AND COMPOSITION COMPRISING THE SAME | BRIDGESTONE CORPORATION (JP) | 2002-05-16 | — | — | WO | claimed |
| US-20020035195-A1 | Viscosity-stabilizer-containing natural rubber latex and natural rubber and a production process thereof | BRIDGESTONE CORPORATION | 2002-03-21 | — | — | US | claimed |
| WO-2000009131-A1 | DIAMINOPYRIMIDINES AND COMBINATION THERAPIES EFFECTIVE FOR TREATMENT OF P-GLYCOPROTEIN POSITIVE CANCERS | WARNER-LAMBERT COMPANY (US) | 2000-02-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006042-A1 | Diaminopyrimidines and combination therapies effective for treatment of P-glycoprotein positive cancers | ABCB1, ABCC1, DPYD | HDAC8 3342/4885HDAC6 2140/4885EPHX1 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.