Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128885 | 0.98 | SMN1; SMN2 (0.63) | SMN1; SMN2TSHRCASP1ABL1CYP3A4 | |
| SCHEMBL28303002 | 0.96 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRCASP1ABL1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6750016 | 0.96 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRCASP1ABL1CYP3A4 | |
| Ethane SCHEMBL11678007 | 0.94 | ABL1 (0.62) | SMN1; SMN2TSHRCASP1ABL1CYP3A4 | |
| Nitrogen SCHEMBL28649098 | 0.94 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1ABL1CYP3A4 | |
| 3,5-Dichloroanthranilic Acid SCHEMBL10496322 | 0.84 | TSHR (0.58) | SMN1; SMN2TSHRCASP1ABL1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL2320305 | 0.83 | ALDH1A1 (0.61) | SMN1; SMN2TSHRCASP1CYP3A4ALDH1A1 | |
| SCHEMBL2722648 | 0.82 | PPM1B (0.67) | SMN1; SMN2TSHRCASP1ABL1CYP3A4 | |
| 3-Aminobenzoic Acid SCHEMBL10434170 | 0.82 | PBRM1 (0.47) | SMN1; SMN2TSHRCASP1ABL1CYP3A4 | |
| SCHEMBL31542015 | 0.81 | ALDH1A1 (0.63) | SMN1; SMN2TSHRCASP1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466907-B1 | PROCESS FOR PRODUCING QUINAZOLIN-4-ONE AND DERIVATIVE THEREOF | UBE INDUSTRIES (JP) | 2011-08-10 | — | — | EP | disclosed |
| US-7232903-B2 | Process for producing quinazolin-4-one and derivatives thereof | UBE INDUSTRIES, LTD. (JP) | 2007-06-19 | — | — | US | disclosed |
| US-20050124809-A1 | Process for producing quinazolin-4-one and derivatives thereof | UBE INDUSTRIES, LTD. (JP) | 2005-06-09 | — | — | US | disclosed |
| EP-1466907-A1 | PROCESS FOR PRODUCING QUINAZOLIN-4-ONE AND DERIVATIVE THEREOF | Ube Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124809-A1 | Process for producing quinazolin-4-one and derivatives thereof | ASNS, NQO2, KYNU | SMN1; SMN2 4739/4885TSHR 4406/4885CASP1 558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.