Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 7/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4523623 | 0.76 | SCN4A (0.58) | SCN4ATAAR1 | |
| SCHEMBL16133830 | 0.76 | SCN4A (0.58) | SCN4ATAAR1 | |
| Hydrochloric Acid SCHEMBL8320866 | 0.74 | SCN4A (0.56) | SCN4A | |
| Hydrochloric Acid SCHEMBL14893289 | 0.74 | SCN4A (0.56) | SCN4A | |
| SCHEMBL14143114 | 0.74 | TAAR1 (0.57) | SCN4AHTR2AHRH1TAAR1GBA1 | |
| SCHEMBL24724279 | 0.74 | TAAR1 (0.57) | SCN4AHTR2AHRH1TAAR1GBA1 | |
| SCHEMBL8227223 | 0.74 | TAAR1 (0.57) | SCN4AHTR2AHRH1TAAR1GBA1 | |
| SCHEMBL30757891 | 0.73 | SCN4A (0.47) | SCN4AHTR2ATAAR1 | |
| SCHEMBL11403598 | 0.71 | HTR2A (0.67) | HTR2AHRH1SLC6A3 | |
| SCHEMBL9299256 | 0.68 | MAOA (0.61) | SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3799871-A2 | PYRAZOL-3-ONES THAT ACTIVATE PRO-APOTOTIC BAX | Dana Farber Cancer Institute, Inc. (US) | 2021-04-07 | — | — | EP | disclosed |