Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | SCN4A | P35499 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2396587 | 0.82 | SCN4A (0.51) | MAOAMAOBSCN4AALDH1A1 | |
| SCHEMBL7529147 | 0.79 | MAOA (0.68) | MAOAMAOBSCN4AALDH1A1MAPK1 | |
| SCHEMBL11383818 | 0.78 | SCN4A (0.54) | MAOAMAOBSCN4AMAPK1DPP4 | |
| SCHEMBL4523623 | 0.77 | SCN4A (0.58) | MAOAMAOBSCN4ADPP4F2 | |
| SCHEMBL16133830 | 0.77 | SCN4A (0.58) | MAOAMAOBSCN4ADPP4F2 | |
| SCHEMBL8909149 | 0.76 | MAOA (1.00) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| SCHEMBL4099623 | 0.76 | MAOA (1.00) | MAOAMAOBALDH1A1MAPK1MTNR1A | |
| Hydrochloric Acid SCHEMBL8320866 | 0.76 | SCN4A (0.56) | MAOAMAOBSCN4AALDH1A1DPP4 | |
| Hydrochloric Acid SCHEMBL14893289 | 0.76 | SCN4A (0.56) | MAOAMAOBSCN4AALDH1A1DPP4 | |
| Hydrochloric Acid SCHEMBL9872076 | 0.75 | ALDH1A1 (0.48) | MAOAMAOBSCN4AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280027-A | Quinazoline containing compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |
| EP-0459730-A2 | Anti-tumour compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |