Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24273060 | 0.83 | PNMT (0.35) | PNMTOPRL1 | |
| SCHEMBL31387195 | 0.82 | PNMT (0.31) | PNMTOPRL1 | |
| SCHEMBL25361834 | 0.82 | PNMT (0.31) | PNMTOPRL1 | |
| SCHEMBL25357471 | 0.82 | PNMT (0.31) | PNMTOPRL1 | |
| SCHEMBL25358899 | 0.82 | PNMT (0.31) | PNMTOPRL1 | |
| SCHEMBL11949329 | 0.82 | OPRL1 (0.43) | OPRL1RORC | |
| SCHEMBL1808867 | 0.82 | OPRL1 (0.43) | OPRL1 | |
| Hydrochloric Acid SCHEMBL1803833 | 0.81 | OPRL1 (0.43) | OPRL1RORC | |
| SCHEMBL23192442 | 0.78 | OPRL1 (0.33) | OPRL1RORC | |
| SCHEMBL25095242 | 0.78 | RORC (0.34) | OPRL1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3589638-B1 | COMPOUNDS USEFUL FOR INHIBITING ROR-GAMMA-T | LILLY CO ELI (US) | 2021-04-07 | — | — | EP | disclosed |