Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.60 |
| ▸ | MMEL1 | Q495T6 | 6/20 | 0.58 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.56 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.49 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312962 | 1.00 | MME (0.60) | MMEMMEL1FFAR2ERCC1ERCC4 | |
| SCHEMBL2319342 | 0.90 | FFAR2 (0.72) | MMEMMEL1FFAR2PRSS1PRSS2 | |
| SCHEMBL2319336 | 0.90 | FFAR2 (0.72) | MMEMMEL1FFAR2PRSS1PRSS2 | |
| SCHEMBL2313157 | 0.89 | FFAR2 (0.62) | MMEMMEL1FFAR2ERCC1ERCC4 | |
| SCHEMBL2313155 | 0.89 | FFAR2 (0.62) | MMEMMEL1FFAR2ERCC1ERCC4 | |
| SCHEMBL2312992 | 0.89 | MME (0.51) | MMEMMEL1FFAR2ERCC1ERCC4 | |
| SCHEMBL2313004 | 0.89 | MME (0.51) | MMEMMEL1FFAR2ERCC1ERCC4 | |
| SCHEMBL2317678 | 0.88 | MME (0.60) | MMEMMEL1FFAR2MEN1KMT2A | |
| SCHEMBL2317684 | 0.88 | MME (0.60) | MMEMMEL1FFAR2MEN1KMT2A | |
| SCHEMBL2314959 | 0.85 | MME (0.71) | MMEMMEL1FFAR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |