Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.32 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | CTSA | P10619 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23905423 | 0.88 | GRM2 (0.31) | KCNH2 | |
| SCHEMBL23905308 | 0.88 | GRM2 (0.31) | KCNH2 | |
| SCHEMBL24984672 | 0.81 | CNR2 (0.33) | CNR2TRPV1TGFBR1TGFBR2CASP1 | |
| SCHEMBL24984667 | 0.81 | TRPV1 (0.35) | CNR2TRPV1TGFBR1TGFBR2CASP1 | |
| SCHEMBL24985729 | 0.81 | TRPV1 (0.35) | CNR2TRPV1TGFBR1TGFBR2CASP1 | |
| SCHEMBL26569820 | 0.81 | CNR2 (0.30) | CNR2 | |
| SCHEMBL26526274 | 0.81 | TRPV1 (0.34) | CNR2TRPV1TGFBR1TGFBR2CASP1 | |
| SCHEMBL24984696 | 0.79 | TGFBR1 (0.33) | CNR2TRPV1TGFBR1TGFBR2CASP1 | |
| SCHEMBL24984694 | 0.79 | TGFBR1 (0.33) | CNR2TRPV1TGFBR1TGFBR2CASP1 | |
| SCHEMBL23905511 | 0.77 | CFTR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021066922-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ENANTA PHARMACEUTICALS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |