Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 3/20 | 0.35 |
| ▸ | LATS1 | O95835 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196149 | 1.00 | GRM2 (0.38) | GRM2CFTRLATS1PDE3BPDE3A | |
| SCHEMBL23196094 | 0.92 | GRM2 (0.37) | GRM2CFTRLATS1PDE3BPDE3A | |
| SCHEMBL23905424 | 0.90 | GRM2 (0.36) | GRM2CFTRLATS1PDE3BPDE3A | |
| SCHEMBL26537778 | 0.89 | GRM2 (0.34) | GRM2CFTRPDE3BPDE3AHDAC1 | |
| SCHEMBL23195598 | 0.89 | GRM2 (0.34) | GRM2CFTRPDE3BPDE3AHDAC1 | |
| SCHEMBL23196044 | 0.89 | GRM2 (0.35) | GRM2CFTRLATS1PDE3BPDE3A | |
| SCHEMBL23195889 | 0.88 | GRM2 (0.38) | GRM2CFTRLATS1PDE3BPDE3A | |
| SCHEMBL24985735 | 0.88 | GRM2 (0.38) | GRM2CFTRLATS1PDE3BPDE3A | |
| SCHEMBL31412382 | 0.88 | GRM2 (0.38) | GRM2CFTRLATS1PDE3BPDE3A | |
| SCHEMBL23905656 | 0.83 | CFTR (0.37) | GRM2CFTRLATS1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230125803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ENANTA PHARM INC (US) | 2023-04-27 | — | — | US | disclosed |
| WO-2021066922-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ENANTA PHARMACEUTICALS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230125803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ACE, HPRT1, ACE2 | GRM2 4163/4885CFTR 283/4885LATS1 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.