Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196147 | 0.90 | GRM2 (0.38) | GRM2CFTRSCN9ALATS1PDE3B | |
| SCHEMBL23196149 | 0.90 | GRM2 (0.38) | GRM2CFTRSCN9ALATS1PDE3B | |
| SCHEMBL23905434 | 0.89 | CTSS (0.35) | GRM2CFTRSCN9APDE3BPDE3A | |
| SCHEMBL23196094 | 0.89 | GRM2 (0.37) | GRM2CFTRSCN9ALATS1PDE3B | |
| SCHEMBL23905656 | 0.81 | CFTR (0.37) | GRM2CFTRLATS1PDE3BPDE3A | |
| SCHEMBL23195598 | 0.80 | GRM2 (0.34) | GRM2CFTRPDE3BPDE3AHDAC1 | |
| SCHEMBL26537778 | 0.80 | GRM2 (0.34) | GRM2CFTRPDE3BPDE3AHDAC1 | |
| SCHEMBL23196044 | 0.79 | GRM2 (0.35) | GRM2CFTRLATS1PDE3BPDE3A | |
| SCHEMBL23883068 | 0.79 | CFTR (0.36) | CFTRSCN9ACYP2C9IDO1TRPV1 | |
| SCHEMBL23883066 | 0.79 | CFTR (0.36) | CFTRSCN9ACYP2C9IDO1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021198981-A1 | ANTIVIRAL COMPOUNDS AND USES THEREOF | Janssen Biopharma, Inc. (US) | 2021-10-07 | — | — | WO | disclosed |