Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 3/20 | 0.33 |
| ▸ | XBP1 | P17861 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12257761 | 0.74 | KDM4E (0.32) | TDP1MEN1KMT2AKDM4E | |
| SCHEMBL2189906 | 0.74 | KDM4E (0.32) | TDP1MEN1KMT2AKDM4E | |
| SCHEMBL2188168 | 0.72 | MCL1 (0.33) | KDM4E | |
| SCHEMBL23196514 | 0.70 | MAPT (0.35) | MAPTTDP1RECQLXBP1ALDH1A1 | |
| SCHEMBL30571505 | 0.66 | ALDH1A1 (0.50) | MAPTRECQLALDH1A1NPSR1MEN1 | |
| SCHEMBL24660619 | 0.61 | KCNT1 (0.49) | ALDH1A1 | |
| SCHEMBL31360651 | 0.61 | SLC6A3 (0.49) | MAPTTDP1RECQLXBP1ALDH1A1 | |
| SCHEMBL31360696 | 0.61 | GRN (0.53) | MAPTTDP1RECQLXBP1ALDH1A1 | |
| SCHEMBL23849248 | 0.61 | CA1 (0.52) | MAPTNPSR1KMT2AKDM4E | |
| SCHEMBL23607312 | 0.61 | CA1 (0.52) | MAPTNPSR1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021063335-A1 | ERK1/2 PROTEIN KINASE INHIBITOR AND USE THEREOF | 南京药石科技股份有限公司 | 2021-04-08 | — | — | WO | disclosed |