Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23196350 | 0.73 | GAA (0.62) | GAA | |
| SCHEMBL23196336 | 0.72 | ACACB (0.35) | ACACBGAAPOLBIKBKB | |
| SCHEMBL29495691 | 0.71 | PKM (0.32) | — | |
| SCHEMBL22950609 | 0.71 | PKM (0.32) | — | |
| SCHEMBL18444799 | 0.69 | HMOX1 (0.43) | ACACB | |
| SCHEMBL3121668 | 0.67 | PDK2 (0.31) | — | |
| SCHEMBL26337623 | 0.67 | CDK4 (0.38) | ACACB | |
| SCHEMBL3125797 | 0.66 | — | — | |
| SCHEMBL1416493 | 0.66 | ABL1 (0.37) | — | |
| SCHEMBL29397320 | 0.66 | ABL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4023642-A1 | JNK INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021063207-A1 | JNK INHIBITOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 武汉朗来科技发展有限公司 | 2021-04-08 | — | — | WO | disclosed |