SCHEMBL23196467

SCHEMBL23196467

C/C=C(\C)C(=O)NCCCCNC(=O)/C=C/c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.70
EGFR P00533 1/20 0.68
HDAC3 O15379 3/20 0.61
HDAC4 P56524 3/20 0.61
HDAC1 Q13547 3/20 0.61
HDAC7 Q8WUI4 3/20 0.61
HDAC2 Q92769 3/20 0.61
HDAC10 Q969S8 3/20 0.61
HDAC11 Q96DB2 3/20 0.61
HDAC8 Q9BY41 3/20 0.61
HDAC6 Q9UBN7 3/20 0.61
HDAC9 Q9UKV0 3/20 0.61
HDAC5 Q9UQL6 3/20 0.61
LMNA P02545 3/20 0.59
MMP1 P03956 2/20 0.57
MMP2 P08253 2/20 0.57
MMP9 P14780 2/20 0.57
POLB P06746 1/20 0.57
RECQL P46063 1/20 0.57
ALDH1A1 P00352 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27129868 1.00 KMT2A (0.70) KMT2AEGFRHDAC3HDAC4HDAC1
SCHEMBL28735544 1.00 KMT2A (0.70) KMT2AEGFRHDAC3HDAC4HDAC1
SCHEMBL31344555 0.99 EGFR (0.71) KMT2AEGFRHDAC3HDAC4HDAC1
SCHEMBL27145242 0.88 KMT2A (0.65) KMT2AEGFRHDAC3HDAC4HDAC1
SCHEMBL27029454 0.88 KMT2A (0.65) KMT2AEGFRHDAC3HDAC4HDAC1
SCHEMBL31140946 0.88 EGFR (0.67) KMT2AEGFRHDAC3HDAC4HDAC1
SCHEMBL3208177 0.87 KMT2A (0.93) KMT2AEGFRHDAC3HDAC4HDAC1
SCHEMBL31140919 0.86 KMT2A (0.70) KMT2AEGFRHDAC3HDAC4HDAC1
SCHEMBL31344548 0.86 EGFR (0.55) KMT2AEGFRHDAC3HDAC4HDAC1
SCHEMBL6415859 0.85 KMT2A (0.90) KMT2AEGFRHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346556-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2025-11-13 US claimed
US-12384742-B2 Organic compounds GIVAUDAN SA (CH) 2025-08-12 US claimed
EP-4507522-A1 TASTE MODIFYING COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2025-02-19 EP claimed
CN-119421642-A Taste modifying composition and use thereof 弗门尼舍有限公司 2025-02-11 CN claimed
WO-2023247332-A1 TASTE MODIFYING COMPOSITIONS AND USES THEREOF FIRMENICH SA (CH) 2023-12-28 WO claimed
US-20220332675-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2022-10-20 US claimed
US-20250346556-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2025-11-13 US disclosed
US-12384742-B2 Organic compounds GIVAUDAN SA (CH) 2025-08-12 US disclosed
EP-4507522-A1 TASTE MODIFYING COMPOSITIONS AND USES THEREOF Firmenich SA (CH) 2025-02-19 EP disclosed
CN-119421642-A Taste modifying composition and use thereof 弗门尼舍有限公司 2025-02-11 CN disclosed
US-20240315299-A1 AMIDE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH INCORPORATED (US) 2024-09-26 US disclosed
EP-4307921-A1 AMIDE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS Firmenich Incorporated (US) 2024-01-24 EP disclosed
WO-2023247332-A1 TASTE MODIFYING COMPOSITIONS AND USES THEREOF FIRMENICH SA (CH) 2023-12-28 WO disclosed
WO-2022231918-A1 AMIDE COMPOUNDS AND THEIR USE AS FLAVOR MODIFIERS FIRMENICH INCORPORATED (US) 2022-11-03 WO disclosed
US-20220332675-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2022-10-20 US disclosed
WO-2021063942-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2021-04-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346556-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS NUDT1, OGT, AOC3 KMT2A 876/4885EGFR 4639/4885HDAC3 3952/4885
US-12384742-B2 Organic compounds NUDT1, CNOT9, SOST KMT2A 577/4885EGFR 4540/4885HDAC3 2762/4885
US-20220332675-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS NUDT1, OGT, AOC3 KMT2A 897/4885EGFR 4581/4885HDAC3 3952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.