Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298514 | 0.85 | — | — | |
| SCHEMBL2821588 | 0.80 | SOAT1 (0.48) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL1418707 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL247694 | 0.79 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| Water SCHEMBL27569536 | 0.78 | SOAT1 (0.46) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL14934920 | 0.77 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL18979198 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL29896398 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| Water SCHEMBL1097795 | 0.76 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10NPSR1GLO1 | |
| SCHEMBL8630186 | 0.76 | ALDH1A1 (0.52) | ALDH1A1LMNAHSD17B10NPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130029378-A1 | NOVEL ENZYME | ISIS INNOVATION LIMITED (GB) | 2013-01-31 | — | — | US | disclosed |
| EP-2356226-A2 | NOVEL ENZYME | ISIS INNOVATION LIMITED (GB) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010041055-A2 | NOVEL ENZYME | ISIS INNOVATION LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |
| US-20100086958-A1 | NOVEL ENZYME | ISIS INNOVATION LIMITED (GB) | 2010-04-08 | — | — | US | disclosed |