Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23197769 | 0.85 | TP53 (0.49) | TP53L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL23198944 | 0.82 | TP53 (0.46) | TP53L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL23198467 | 0.78 | TP53 (0.42) | TP53L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL18665944 | 0.75 | TP53 (0.56) | TP53L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL2288364 | 0.75 | MAPT (0.64) | TP53L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL28825701 | 0.74 | L3MBTL1 (0.59) | TP53L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL23720127 | 0.73 | L3MBTL1 (0.58) | TP53L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL3826992 | 0.72 | MAPT (0.60) | TP53L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL505220 | 0.72 | RXFP1 (0.69) | TP53L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL19766263 | 0.72 | L3MBTL1 (0.61) | TP53L3MBTL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021064077-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-08 | — | — | WO | disclosed |