Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.30 |
| ▸ | CDC25B | P30305 | 3/20 | 0.30 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.30 |
| ▸ | CDC25A | P30304 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23197895 | 0.88 | PTPN1 (0.34) | PTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL23191932 | 0.74 | FOLH1 (0.39) | FOLH1DGAT1PTPN1CDC25BPTPN2 | |
| SCHEMBL23191929 | 0.69 | PTPN1 (0.35) | FOLH1PTPN1CDC25BPTPN2CDC25A | |
| SCHEMBL23197894 | 0.63 | KDM4E (0.30) | — | |
| SCHEMBL19389395 | 0.61 | OPRM1 (0.31) | — | |
| SCHEMBL16350583 | 0.60 | CA1 (0.43) | — | |
| SCHEMBL21652481 | 0.60 | CA1 (0.46) | — | |
| SCHEMBL13224654 | 0.60 | RORC (0.45) | — | |
| SCHEMBL21652483 | 0.60 | CA1 (0.46) | — | |
| SCHEMBL19017944 | 0.60 | HSD17B10 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067738-A1 | DEVELOPMENT OF IMAGING AND THERAPEUTIC GLUCOSE ANALOGUES FOR SODIUM DEPENDENT GLUCOSE TRANSPORTERS | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2021-04-08 | — | — | WO | disclosed |