SCHEMBL23199040

SCHEMBL23199040

OCc1ccc2cc3ccccc3cc2c1O

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
HIF1A Q16665 1/20 0.45
CYP1B1 Q16678 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130289 0.84 PTPN22 (0.58)
SCHEMBL30241839 0.81 ALDH1A1 (0.45) ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL3053971 0.81 ALDH1A1 (0.45) ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL13066116 0.79 ALDH1A1 (0.43) ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL3048060 0.79 ALDH1A1 (0.43) ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL3043087 0.79 ALDH1A1 (0.43) ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL11316967 0.79 ALDH1A1 (0.44) ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL136100 0.78 ALDH1A1 (0.46) ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL11757019 0.77 PTPN22 (0.48) ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL11825062 0.76 TYR (0.47) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3801507-A2 TOMM6-INTERACTING EXTRACTS AND COMPOUNDS FOR USE IN THE TREATMENT AND PROPHYLAXIS OF NERVOUS SYSTEM DISEASES, ATHEROSCLEROSIS, HEPATITIS B INFECTION AND HUMAN PAPILLOMA VIRUS (HPV) INFECTION ETH Zurich (CH) 2021-04-14 EP disclosed