Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938199 | 0.89 | PDGFRB (0.41) | HTR1AHTR1BHTR1DALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL23199823 | 0.88 | PDGFRB (0.40) | HTR1AHTR1BHTR1DALDH1A1KMT2A | |
| SCHEMBL9938547 | 0.88 | KDM4E (0.40) | HTR1AHTR1BHTR1DALDH1A1KMT2A | |
| SCHEMBL30645497 | 0.84 | KMT2A (0.42) | HTR1AHTR1BALDH1A1KMT2AKDM4E | |
| SCHEMBL668901 | 0.81 | CA12 (0.41) | ALDH1A1KMT2AKDM4EGLAGAA | |
| SCHEMBL996026 | 0.81 | CA12 (0.41) | ALDH1A1KMT2AKDM4EGLAGAA | |
| SCHEMBL23199812 | 0.81 | SMN1; SMN2 (0.39) | THRAALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL30352755 | 0.80 | PDGFRB (0.35) | ALDH1A1KMT2AKDM4EGLAGAA | |
| SCHEMBL9938274 | 0.78 | ELANE (0.38) | HTR1BHTR1DALDH1A1LMNAHSD17B10 | |
| SCHEMBL9938614 | 0.78 | MEN1 (0.42) | HTR1BHTR1DKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801553-A2 | PRODRUGS OF FULVESTRANT | Kashiv Biosciences, LLC (US) | 2021-04-14 | — | — | EP | disclosed |