Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23199806 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL12467986 | 0.86 | ACHE (0.47) | MAPK1ALDH1A1CYP1A2MAPTLMNA | |
| SCHEMBL23199818 | 0.81 | HTR1A (0.35) | SMN1; SMN2MAOAMAOBL3MBTL1ALDH1A1 | |
| SCHEMBL9938547 | 0.79 | KDM4E (0.40) | SMN1; SMN2MAOAMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL30645497 | 0.78 | KMT2A (0.42) | SMN1; SMN2MAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL30846904 | 0.77 | GLA (0.39) | L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL30352755 | 0.76 | PDGFRB (0.35) | SMN1; SMN2MAOAALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9938199 | 0.76 | PDGFRB (0.41) | MAOAL3MBTL1ALDH1A1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL23199823 | 0.75 | PDGFRB (0.40) | MAOAL3MBTL1ALDH1A1KMT2ALMNA | |
| SCHEMBL996026 | 0.75 | CA12 (0.41) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3801553-A2 | PRODRUGS OF FULVESTRANT | Kashiv Biosciences, LLC (US) | 2021-04-14 | — | — | EP | disclosed |