SCHEMBL23199831

SCHEMBL23199831

CN1CCC(NC(=O)Cl)CC1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 2/20 0.43
P2RX4 Q99571 1/20 0.43
SSTR4 P31391 3/20 0.41
SIGMAR1 Q99720 1/20 0.40
SSTR1 P30872 1/20 0.40
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL508551 0.80 ATM (0.45) KDM4EALDH1A1P2RX4SSTR4SIGMAR1
SCHEMBL2016562 0.80 KDM4E (0.49) KDM4EALDH1A1P2RX4SSTR4SIGMAR1
SCHEMBL26369198 0.79 KDM4E (0.41) KDM4EALDH1A1P2RX4SSTR4SIGMAR1
SCHEMBL1490713 0.78 KDM4E (0.43) KDM4EALDH1A1P2RX4SSTR4SIGMAR1
SCHEMBL19457387 0.78 KDM4E (0.43) KDM4EALDH1A1P2RX4SSTR4SIGMAR1
SCHEMBL15796814 0.78 KDM4E (0.43) KDM4EALDH1A1P2RX4SSTR4SIGMAR1
SCHEMBL8647513 0.78
SCHEMBL12789742 0.78 ALDH1A1 (0.50) KDM4EALDH1A1P2RX4SSTR4SIGMAR1
SCHEMBL10271099 0.77 EPHX2 (0.46) KDM4EALDH1A1P2RX4
SCHEMBL22906115 0.77 KDM4E (0.45) KDM4EALDH1A1P2RX4SSTR4SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3801553-B1 PRODRUGS OF FULVESTRANT KASHIV BIOSCIENCES LLC (US) 2026-03-25 EP disclosed
US-20210253626-A1 PRODRUGS OF FULVESTRANT KI PHARMACEUTICALS, LLC 2021-08-19 US disclosed
EP-3801553-A2 PRODRUGS OF FULVESTRANT Kashiv Biosciences, LLC (US) 2021-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253626-A1 PRODRUGS OF FULVESTRANT CYP19A1, PGR, CYP21A2 KDM4E 775/4885ALDH1A1 746/4885P2RX4 1339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.