Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23201272 | 0.89 | PPARG (0.46) | PRMT5WDR77PPARGL3MBTL1CHRM4 | |
| SCHEMBL23490771 | 0.83 | TLR2 (0.45) | SLC18A3PPARGCHRM4CHRM2CHRM5 | |
| SCHEMBL8922008 | 0.80 | CHRM4 (0.59) | PRMT5WDR77SLC18A3L3MBTL1CHRM4 | |
| SCHEMBL7672219 | 0.79 | RAB9A (0.50) | L3MBTL1ACEACE2BCHE | |
| SCHEMBL4748923 | 0.79 | RAB9A (0.50) | L3MBTL1ACEACE2BCHE | |
| SCHEMBL5491802 | 0.79 | RAB9A (0.50) | L3MBTL1ACEACE2BCHE | |
| SCHEMBL18065023 | 0.79 | RAB9A (0.42) | L3MBTL1TACR1ACEACE2ECE1 | |
| SCHEMBL23116494 | 0.78 | HTRA1 (0.49) | AGTR2 | |
| SCHEMBL15030122 | 0.78 | HTRA1 (0.49) | AGTR2 | |
| SCHEMBL23116487 | 0.78 | HTRA1 (0.49) | AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802489-A2 | MASP-2 INHIBITORS AND METHODS OF USE | Omeros Corporation (US) | 2021-04-14 | — | — | EP | disclosed |