Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324651 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL6156438 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL8189003 | 0.79 | ALDH1A1 (0.60) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL8724146 | 0.77 | MAPT (0.43) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL95531 | 0.77 | TSHR (0.42) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL678299 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2AAR | |
| SCHEMBL2321667 | 0.76 | FFAR1 (0.48) | MEN1KMT2ACYP3A4PTPN11HTT | |
| SCHEMBL7379264 | 0.74 | KCNK3 (0.71) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL28886 | 0.74 | APP (0.35) | ALDH1A1MAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL4098064 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |