Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 10/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23201985 | 0.86 | SLC22A12 (0.44) | MTNR1AHDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL23203035 | 0.78 | HDAC1 (0.43) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL17165055 | 0.77 | HDAC6 (0.64) | MTNR1AHDAC6HDAC1HDAC2HDAC10 | |
| SCHEMBL23202566 | 0.69 | HDAC6 (0.43) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL29779623 | 0.67 | HDAC3 (0.41) | HDAC6HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL23167369 | 0.67 | HDAC3 (0.41) | HDAC6HDAC1HDAC2HDAC8HDAC4 | |
| SCHEMBL23202570 | 0.67 | PTGDR2 (0.44) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL23201965 | 0.67 | HDAC6 (0.52) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL18108896 | 0.66 | HDAC6 (0.52) | HDAC6HDAC1HDAC2HDAC10HDAC8 | |
| SCHEMBL2543931 | 0.66 | MTNR1A (0.55) | MTNR1ASLC22A12PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067859-A1 | 5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF | TENAYA THERAPEUTICS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |