Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23202570 | 0.89 | PTGDR2 (0.44) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL23203467 | 0.78 | MTNR1A (0.46) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL23202566 | 0.71 | HDAC6 (0.43) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL23201965 | 0.70 | HDAC6 (0.52) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL23203083 | 0.66 | HDAC1 (0.44) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL23201985 | 0.64 | SLC22A12 (0.44) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL6489659 | 0.62 | HDAC6 (0.61) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL23167201 | 0.61 | HDAC6 (0.70) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL12472746 | 0.61 | HDAC6 (1.00) | HDAC1HDAC6HDAC8HDAC3HDAC2 | |
| SCHEMBL21695124 | 0.60 | PTGDR2 (0.75) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067859-A1 | 5-FLUORONICOTINAMIDE DERIVATIVES AND USES THEREOF | TENAYA THERAPEUTICS, INC. (US) | 2021-04-08 | — | — | WO | disclosed |