SCHEMBL2320428

SCHEMBL2320428

O=C(O)C[C@H](Cc1ccc(C(F)(F)F)cc1)NC(=O)Cc1ccc2ccccc2c1

nearest known ligand 0.73

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 10/20 0.73
PIN1 Q13526 2/20 0.60
MME P08473 3/20 0.55
RIOK2 Q9BVS4 1/20 0.51
UTS2R Q9UKP6 1/20 0.51
CNR2 P34972 1/20 0.50
NR1H4 Q96RI1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2320431 1.00 FFAR2 (0.73) FFAR2PIN1MMERIOK2UTS2R
SCHEMBL2315141 0.90 FFAR2 (0.67) FFAR2PIN1MMEUTS2RCNR2
SCHEMBL2314874 0.90 PIN1 (0.74) FFAR2PIN1MMERIOK2CNR2
SCHEMBL2315266 0.90 PIN1 (0.74) FFAR2PIN1MMERIOK2CNR2
SCHEMBL2320231 0.90 PIN1 (0.74) FFAR2PIN1MMERIOK2CNR2
SCHEMBL2314866 0.90 PIN1 (0.74) FFAR2PIN1MMERIOK2CNR2
SCHEMBL2320240 0.90 PIN1 (0.74) FFAR2PIN1MMERIOK2CNR2
SCHEMBL2364855 0.89 FFAR2 (0.77) FFAR2PIN1MMECNR2
SCHEMBL2364853 0.89 FFAR2 (0.77) FFAR2PIN1MMECNR2
SCHEMBL2312671 0.88 FFAR2 (0.74) FFAR2PIN1MMECNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092284-A1 NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS EUROSCREEN S.A. (BE) 2011-08-04 WO claimed