Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21704463 | 0.88 | L3MBTL1 (0.64) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL23162595 | 0.86 | ADORA2B (0.57) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL29623173 | 0.86 | ADORA2B (0.57) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL21704471 | 0.84 | ADORA2B (0.58) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL21704319 | 0.79 | L3MBTL1 (0.67) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL29623178 | 0.77 | ADORA2B (0.57) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL23204450 | 0.77 | ADORA2B (0.57) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL7147842 | 0.77 | ADORA2B (0.57) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL29623513 | 0.77 | ADORA2B (0.57) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL23162622 | 0.75 | ADORA2B (0.54) | ADORA2BL3MBTL1ALDH1A1PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021063852-A1 | SUBSTITUTED PYRIMIDINE FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2021-04-08 | — | — | WO | disclosed |