Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531442 | 0.85 | KMT2A (0.49) | TDP1MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL4233955 | 0.84 | NOX4 (0.49) | TDP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8280283 | 0.83 | HSD17B10 (0.53) | TDP1MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL14439930 | 0.82 | POLB (0.50) | TDP1MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL31444647 | 0.82 | LMNA (0.51) | TDP1MEN1KMT2AMAPTPOLB | |
| SCHEMBL2528182 | 0.81 | CYP1A2 (0.64) | MEN1KMT2AHSD17B10MAPTRORC | |
| SCHEMBL7126585 | 0.81 | HSD17B10 (0.55) | MEN1KMT2AHSD17B10MAPTRORC | |
| SCHEMBL3266897 | 0.81 | CYP1A2 (0.64) | MEN1KMT2AHSD17B10MAPTRORC | |
| SCHEMBL30402470 | 0.81 | HSD17B10 (0.55) | TDP1MEN1KMT2AHSD17B10MAPT | |
| SCHEMBL31534620 | 0.80 | TDP1 (0.57) | TDP1MEN1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021066608-A1 | COMPOUND FOR INDUCING EXPRESSION OF ANTI-AGING GENE KLOTHO AND USE THEREOF | 주식회사 클로소사이언스 | 2021-04-08 | — | — | WO | disclosed |