⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41775 | 0.83 | TSHR (0.67) | — | |
| SCHEMBL2686386 | 0.81 | TSHR (0.50) | — | |
| Formaldehyde SCHEMBL8673672 | 0.80 | TSHR (0.56) | — | |
| SCHEMBL577627 | 0.77 | CA2 (0.59) | — | |
| SCHEMBL31672218 | 0.76 | TSHR (0.59) | — | |
| SCHEMBL10952838 | 0.73 | GFER (0.47) | — | |
| SCHEMBL7539245 | 0.73 | CHKA (0.58) | — | |
| SCHEMBL679970 | 0.73 | MKNK1 (0.56) | — | |
| SCHEMBL11310791 | 0.73 | MKNK1 (0.56) | — | |
| SCHEMBL260498 | 0.73 | TSHR (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 457 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043298-A | (Hetero) aryl-substituted bisphenol compound and thermoplastic resin | 罗伊特化学仪器制造公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117940399-A | Heteroaryl or aryl substituted bisphenol compounds and thermoplastic resins | 三菱瓦斯化学株式会社 | 2024-04-26 | — | — | CN | claimed |
| CN-109415401-B | Nucleic acid complexes | 协和麒麟株式会社 | 2023-02-03 | — | — | CN | claimed |
| US-20220390459-A1 | RAPID, HIGH-INTENSITY CHEMILUMINESCENT DIOXETANES | BECKMAN COULTER, INC. | 2022-12-08 | — | — | US | claimed |
| CN-114867716-A | Fast, high intensity chemiluminescent dioxetanes | 贝克曼库尔特有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-110248939-B | Tyrosine amide derivatives as RHO-kinase inhibitors | 奇斯药制品公司 | 2022-05-17 | — | — | CN | claimed |
| CN-109958001-B | Bactericidal polymer nanofiber aggregate and dry type toilet paper using same | 埃立坦株式会社 | 2021-09-14 | — | — | CN | claimed |
| WO-2021086977-A1 | RAPID, HIGH-INTENSITY CHEMILUMINESCENT DIOXETANES | BECKMAN COULTER, INC. (US) | 2021-05-06 | — | — | WO | claimed |
| US-10954236-B2 | Tyrosine amide derivatives as Rho-Kinase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2021-03-23 | — | — | US | claimed |
| EP-3573987-B1 | TYROSINE AMIDE DERIVATIVES AS RHO- KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2021-03-10 | — | — | EP | claimed |
| WO-1997008150-A1 | SUBSTITUTED CYCLIC UREAS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-03-06 | — | — | WO | claimed |
| WO-1996029329-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-26 | — | — | WO | claimed |
| US-5559110-A | HIV ANTIVIRAL, GOOD SYSTEMIC ABSORPTION ADMINISTERED BY MOUTH | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-24 | — | — | US | claimed |
| US-5543517-A | VIRICIDES | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-08-06 | — | — | US | claimed |
| EP-0686151-A1 | SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-12-13 | — | — | EP | claimed |
| WO-1994019329-A1 | SUBSTITUTED CYCLIC CARBONYLS AND DERIVATIVES THEREOF USEFUL AS RETROVIRAL PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-09-01 | — | — | WO | claimed |
| EP-0607334-A1 | CYCLIC UREAS AND ANALOGUES USEFUL AS RETROVIRAL PROTEASE INHIBITIORS. | DU PONT MERCK PHARMA (US) | 1994-07-27 | — | — | EP | claimed |
| WO-1993007128-A1 | CYCLIC UREAS AND ANALOGUES USEFUL AS RETROVIRAL PROTEASE INHIBITIORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-04-15 | — | — | WO | claimed |
| US-4831041-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-05-16 | — | — | US | claimed |
| EP-0268989-A1 | Imidazopyridine compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | claimed |