Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | VHL | P40337 | 1/20 | 0.46 |
| ▸ | ELOC | Q15369 | 1/20 | 0.46 |
| ▸ | ELOB | Q15370 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11318432 | 1.00 | TSHR (0.56) | TSHRESR1ESR2HDAC8PRSS1 | |
| SCHEMBL41775 | 0.89 | TSHR (0.67) | TSHRESR1ESR2PRSS1PRSS2 | |
| SCHEMBL2288601 | 0.88 | TSHR (0.78) | TSHRESR1ESR2TDP1VHL | |
| SCHEMBL17826366 | 0.88 | ESR1 (0.78) | TSHRESR1ESR2HDAC8ALDH1A1 | |
| SCHEMBL12002490 | 0.86 | HDAC8 (0.46) | TSHRESR1ESR2HDAC8PRSS1 | |
| SCHEMBL8992802 | 0.86 | SRD5A2 (0.50) | TSHRESR1ESR2HDAC8PRSS1 | |
| SCHEMBL8992959 | 0.86 | IDO1 (0.46) | TSHRESR1ESR2HDAC8ALDH1A1 | |
| SCHEMBL9891695 | 0.84 | TSHR (0.48) | TSHRESR1ESR2HDAC8PRSS1 | |
| SCHEMBL24197429 | 0.82 | HDAC8 (0.56) | TSHRESR1ESR2HDAC8ALDH1A1 | |
| SCHEMBL11576495 | 0.82 | TSHR (0.52) | TSHRESR1ESR2HDAC8PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208464-A | POLYESTERIMIDES | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1980-06-17 | — | — | US | claimed |
| US-4101488-A | POLYESTERIMIDE RESIN | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1978-07-18 | — | — | US | claimed |
| US-4008195-A | POLYESTER | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1977-02-15 | — | — | US | claimed |
| US-4007146-A | POLYESTER | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1977-02-08 | — | — | US | claimed |
| US-3936404-A | Aqueous baking varnishes from carboxylic polyester and carboxylic polyimide, and coated article | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1976-02-03 | — | — | US | claimed |
| WO-2022011211-A1 | DEOXYNOJIRIMYCIN DERIVATIVES AS GLUCOSIDASE INHIBITORS | EMERGENT PRODUCT DEVELOPMENT GAITHERSBURG INC. (US) | 2022-01-13 | — | — | WO | disclosed |
| EP-1491952-B1 | Positive-working photosensitive resin composition, method for producing pattern-formed resin film, semiconductor device, display device, and method for producing the semiconductor device and the display device | SUMITOMO BAKELITE CO (JP) | 2015-10-07 | — | — | EP | disclosed |
| EP-2670726-A1 | POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS | Lord Corporation (US) | 2013-12-11 | — | — | EP | disclosed |
| US-20120202723-A1 | POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS | LORD CORPORATION | 2012-08-09 | — | — | US | disclosed |
| WO-2012106597-A1 | POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS | LORD CORPORATION (US) | 2012-08-09 | — | — | WO | disclosed |
| US-8067440-B2 | Phosphonium salts derivatives and uses thereof | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-11-29 | — | — | US | disclosed |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2011-04-21 | — | — | US | disclosed |
| US-4179423-A | TERTIARY AMINE, TRIOL, TRICARBOXYLIC ACID ANHYDRIDE | SCHENECTADY CHEMICALS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4133787-A | Water soluble polyester resin | SCHENECTADY CHEMICALS, INC. (US) | 1979-01-09 | — | — | US | disclosed |
| US-4105639-A | REACTING AROMATIC DICARBOXYLIC ACID, A DIOL, AND A TRIOL, WIRE ENAMELS | SCHENECTADY CHEMICALS, INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4101488-A | POLYESTERIMIDE RESIN | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |
| US-4008195-A | POLYESTER | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1977-02-15 | — | — | US | disclosed |
| US-4007146-A | POLYESTER | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1977-02-08 | — | — | US | disclosed |
| US-3947471-A | CHROMOGENIC | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-03-30 | — | — | US | disclosed |
| US-3936404-A | Aqueous baking varnishes from carboxylic polyester and carboxylic polyimide, and coated article | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202723-A1 | POLYOLS AND THEIR USE IN HYDROCARBON LUBRICATING AND DRILLING FLUIDS | SCD, MRE11, POLH | TSHR 4167/4885ESR1 890/4885ESR2 1559/4885 |
| US-20110092683-A1 | PHOSPHONIUM SALTS DERIVATIVES AND USES THEREOF | PI4K2A, PIP4K2A, PI4K2B | TSHR 2468/4885ESR1 1936/4885ESR2 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.