SCHEMBL2320528

SCHEMBL2320528

C=CC(=O)OCCc1ccccc1C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.58
FOLH1 Q04609 1/20 0.51
ALDH1A1 P00352 6/20 0.46
TSHR P16473 5/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 2/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 1/20 0.46
HCAR2 Q8TDS4 1/20 0.43
KMT2A Q03164 1/20 0.41
PTK2B Q14289 1/20 0.41
AKR1B10 O60218 1/20 0.41
AKR1B1 P15121 1/20 0.41
MAPT P10636 1/20 0.40
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
HTT P42858 1/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
THRA P10827 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30996364 0.91 THRB (0.55) THRBFOLH1ALDH1A1TSHRTP53
SCHEMBL29612237 0.87 THRB (0.50) THRBFOLH1ALDH1A1TSHRTP53
SCHEMBL57853 0.87 THRB (0.50) THRBFOLH1ALDH1A1TSHRTP53
SCHEMBL26653843 0.87 THRB (0.54) THRBFOLH1ALDH1A1TSHRTP53
SCHEMBL5851207 0.86 THRB (0.53) THRBALDH1A1TSHRTP53HIF1A
SCHEMBL7199611 0.86 THRB (0.50) THRBFOLH1ALDH1A1TSHRTP53
SCHEMBL29445300 0.84 TP53 (0.49) THRBFOLH1ALDH1A1TSHRTP53
SCHEMBL9503992 0.84 THRB (0.54) THRBFOLH1ALDH1A1TSHRTP53
SCHEMBL29619581 0.83 THRB (0.47) THRBFOLH1ALDH1A1TSHRTP53
SCHEMBL6283584 0.83 DCLRE1B (0.54) THRBALDH1A1TSHRTP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912457-B Adhesive resin composition, adhesive sheet, active energy ray-curable adhesive sheet, optical member, laminate for image display device, and image display device 三菱化学株式会社 2023-04-18 CN disclosed
US-10676554-B2 Polymer compound, film obtained by hardening this polymer compound and electronic device comprising this film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-09 US disclosed
EP-2531889-B1 USE OF A PHOTOPOLYMER FORMULATION WITH ESTER-BASED WRITING MONOMERS FOR THE FABRICATION OF HOLOGRAPHIC MEDIA COVESTRO DEUTSCHLAND AG (DE) 2020-06-03 EP disclosed
CN-106535815-B Reactive micro-applicator with metal-containing additives for applying dental adhesives 古莎有限公司 2020-05-29 CN disclosed
CN-110382471-A Polymerizable compound, polymerizable liquid crystal mixture, macromolecule, optical film, optically anisotropic body, polarizing film, display device, antireflection film and compound 日本瑞翁株式会社 2019-10-25 CN disclosed
US-20190211123-A1 POLYMER COMPOUND, FILM OBTAINED BY HARDENING THIS POLYMER COMPOUND AND ELECTRONIC DEVICE COMPRISING THIS FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-07-11 US disclosed
US-9057950-B2 Photopolymer formulation having ester-based writing monomers BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-06-16 US disclosed
US-8937074-B2 Enhancement of the action of anti-infective agents and of central and peripheral nervous system agents and transportation of nucleic acid substances NORTH WEST UNIVERSITY (ZA) 2015-01-20 US disclosed
US-20130336990-A1 ENHANCEMENT OF THE ACTION OF ANTI-INFECTIVE AGENTS AND OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM AGENTS AND TRANSPORTATION OF NUCLEIC ACID SUBSTANCES NORTH WEST UNIVERSITY (ZA) 2013-12-19 US disclosed
EP-2531889-A1 PHOTOPOLYMER FORMULATION HAVING ESTER-BASED WRITING MONOMERS Bayer Intellectual Property GmbH (DE) 2012-12-12 EP disclosed
US-20120301422-A1 ENHANCEMENT OF THE ACTION OF ANTI-INFECTIVE AGENTS AND OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM AGENTS AND TRANSPORTATION OF NUCLEIC ACID SUBSTANCES NORTH WEST UNIVERSITY (ZA) 2012-11-29 US disclosed
WO-2011095442-A1 PHOTOPOLYMER FORMULATION HAVING ESTER-BASED WRITING MONOMERS BAYER MATERIALSCIENCE AG (DE) 2011-08-11 WO disclosed
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120301422-A1 ENHANCEMENT OF THE ACTION OF ANTI-INFECTIVE AGENTS AND OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM AGENTS AND TRANSPORTATION OF NUCLEIC ACID SUBSTANCES HRH2, HRH4, CNR2 THRB 2919/4885FOLH1 3019/4885ALDH1A1 4257/4885
US-20130336990-A1 ENHANCEMENT OF THE ACTION OF ANTI-INFECTIVE AGENTS AND OF CENTRAL AND PERIPHERAL NERVOUS SYSTEM AGENTS AND TRANSPORTATION OF NUCLEIC ACID SUBSTANCES HRH2, HRH4, CNR2 THRB 2919/4885FOLH1 3019/4885ALDH1A1 4257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.