SCHEMBL23205355

SCHEMBL23205355

CC(C)(C)OC(=O)N1CCC(OC2CC(Oc3cc(Br)ccn3)C2)CC1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21405347 1.00 GPR119 (0.53) GPR119
SCHEMBL21456063 1.00 GPR119 (0.53) GPR119
SCHEMBL21644754 0.94 GPR119 (0.51) GPR119
SCHEMBL23205486 0.94 GPR119 (0.51) GPR119
SCHEMBL21673925 0.93 GPR119 (0.47) GPR119
SCHEMBL21644749 0.93 GPR119 (0.47) GPR119
SCHEMBL22156950 0.92 GPR119 (0.53) GPR119
SCHEMBL25278138 0.90 GPR119 (0.45) GPR119
SCHEMBL25626363 0.90 GPR119 (0.45) GPR119
SCHEMBL25252578 0.86 GPR119 (0.52) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023093728-A1 BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF 江苏先声药业有限公司 2023-06-01 WO disclosed
WO-2021067606-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE ARVINAS OPERATIONS, INC. (US) 2021-04-08 WO disclosed