Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318886 | 0.92 | PIK3CD (0.34) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL2319994 | 0.84 | GABRA1 (0.31) | — | |
| SCHEMBL2320556 | 0.83 | MEN1 (0.30) | — | |
| SCHEMBL1874422 | 0.82 | PDE10A (0.37) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL2039642 | 0.81 | SLC34A1 (0.32) | PIK3CAPIK3CD | |
| SCHEMBL2040694 | 0.81 | PDE10A (0.41) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL2320981 | 0.80 | CTSA (0.31) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL2355414 | 0.77 | MEN1 (0.47) | — | |
| SCHEMBL2319119 | 0.75 | GRM8 (0.33) | — | |
| SCHEMBL2321107 | 0.75 | ERN1 (0.39) | PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095459-A1 | PYRIDAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-11 | — | — | WO | claimed |
| WO-2011095459-A1 | PYRIDAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-11 | — | — | WO | disclosed |