Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034329 | 0.83 | PDE10A (0.35) | PDE10ASLC34A1PIK3CAKCNH2PI4KB | |
| SCHEMBL1874422 | 0.83 | PDE10A (0.37) | PDE10ACHEK1PIK3CAMTORPIK3CD | |
| SCHEMBL2039642 | 0.81 | SLC34A1 (0.32) | SLC34A1PIK3CAMTORPIK3CD | |
| SCHEMBL2320569 | 0.81 | PIK3CA (0.35) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL2034115 | 0.80 | PDE10A (0.39) | PDE10ACHEK1 | |
| SCHEMBL2355414 | 0.78 | MEN1 (0.47) | — | |
| SCHEMBL2321107 | 0.76 | ERN1 (0.39) | PIK3CA | |
| SCHEMBL1872289 | 0.75 | NPC1 (0.37) | PDE10ACHEK1PIK3CAPIK3CD | |
| SCHEMBL2320556 | 0.75 | MEN1 (0.30) | — | |
| SCHEMBL3338724 | 0.75 | RAC1 (0.39) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076501-A1 | NOVEL 5-(PYRIDIN-3-YL)-PYRIDANIZE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-30 | — | — | WO | claimed |
| WO-2011076501-A1 | NOVEL 5-(PYRIDIN-3-YL)-PYRIDANIZE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-30 | — | — | WO | disclosed |